Effects and safety of intranasal phototherapy for allergic rhinitis

Phototherapy for Allergic Rhinitis

Effects of intranasal phototherapy on nasal microbial flora in patients with allergic rhinitis.

The objective of this study was to investigate the effect of intranasal phototherapy on nasal microbial flora in patients with allergic rhinitis. This prospective, self-comparised, single blind study was performed on patients with a history of at least two years of moderate-to-severe perennial allergic rhinitis that was not controlled by anti-allergic drugs. Thirty-one perennial allergic rhinit...

Effects of intranasal phototherapy on nasal mucosa in patients with allergic rhinitis.

RATIONALE Rhinophototherapy has been shown to be effective in the treatment of allergic rhinitis. Considering that phototherapy with ultraviolet light (UV) induces DNA damage, it is of outstanding importance to evaluate the damage and repair process in human nasal mucosa. METHODS We have investigated eight patients undergoing intranasal phototherapy using a modified Comet assay technique and ...

Intranasal corticosteroids for allergic rhinitis

• Allergic rhinitis is defined as intermittent (or seasonal) or persistent (or perennial), according to symptom duration and frequency. • Intranasal corticosteroids are the most effective treatment option for moderate-severe symptoms and reduce sneezing, rhinorrhea, itching, post-nasal drip and nasal blockage, and total nasal symptom scores better than antihistamines. • There are currently six ...

Intranasal ciclesonide for allergic rhinitis

Ciclesonide is a novel corticosteroid which is optimized for topical use. It is a pro-drug which is activated locally in the airway mucosa, lipid-conjugated for local retention, and has very high protein binding in circulation leading to low systemic bioavailability. These characteristics should lead to highly selective activity with reduced local and systemic side effects. It has been establis...